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Whole grains

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By: Sean Moloughney

Editor, Nutraceuticals World

Indication: Heart disease in diabetic women

Source: Diabetes Care, February 2006;29(2):207-11.

Research: Researchers examined whether intakes of whole grains and dietary fiber were associated with inflammatory indicators among 902 diabetic women in the Nurses’ Health Study.

Results: After adjustment for age, BMI, lifestyle, and dietary covariates, intakes of whole grains and bran were both associated with significantly decreasing trends of C-reactive protein (CRP) and tumor necrosis factor-alpha receptor 2 (TNF-R2)—which are markers of blood vessel inflammation that have been linked to heart disease. High intake of cereal fiber was also inversely associated with lower levels of CRP and TNF-R2. The concentrations of CRP and TNF-R2 were 18 and 8% lower in the highest quintile of cereal fiber as compared with the lowest quintile. Dietary glycemic index was positively associated with CRP and TNF-R2 levels. Therefore, researchers believe whole grains and a low-glycemic index diet may reduce systemic inflammation among women with type 2 diabetes.

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